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An open-label investigator research trial to study the safety and efficacy of a combination of a pro re nata regimen with fixed interval regimen intravitreal injections of ranibizumab in the treatment of choroidal neovascularization in subjects with neovascular age-related macular degeneration
31/12/2012

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The objective of this project is to explore the safety and efficacy of a combination of a pro re nata regimen with a fixed interval regimen of intravitreal ranibizumab injections in the treatment of choroidal neovascularization (CNV) in subjects with neovascular age related macular degeneration. Hypothesis: This reimen may have a benefit in the range of the monthly regimen but with a significantly smaller mean number of injections.    RESULTATS: The 12-month data presented support the hypothesis that the FUSION regimen for CNV secondary to exudative AMD provides visual benefit in the range of the monthly regimens but with a significantly smaller mean number of injections, even in patients in the current incident population presenting in clinical practices with higher levels of visual acuity, not reflected in previous trials, and therefore avoiding the visual limitations of the pro re nata regimens in AMD.

Intravitreal injectionsDry or atrophic AMDExudative or wet AMDRetina scanAutofluorescenceFluorescein angiographyIndocyanine green angiographyOptical coherence tomography

Author

Dr. Jordi Monés, M.D., Ph.D.
COMB Medical license number: 22.838
Director
Doctor of Medicine and Surgery
Specialist in Ophthalmology
Specialist in Retina, Macula and Vitreorretinal

Last modified: 23 September, 2020 - 10:32