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Что нас отличает от других? 

МЕДИЦИНА 360º

Институт Макулы работает на основе глобального медицинского концепта:

  • Наша главная задача – излечение пациентов
  • Индивидуальный подход для каждого случая
  • Необходимое время для каждого пациента
  • Мы ведем научно-исследовательскую работу для поиска новых методов лечения
+ подробнее

Интегральный подход в лечении предлагает программу эксклюзивных услуг:

  • Психологическая поддержка
  • Консультирование по правильному питанию
  • Консультирование по вспомогательным технологиям
  • Услуги по сопровождению в процессе лечения
И другие возможные услуги. + подробнее

Новости + подробнее

Corona virus: vial with pipette in laboratory
26/06/2020.
MARCADORES SEROLÓGICOS PARA EL DIAGNÓSTICO DE COVID-19
El Institut de la Màcula, junto con el laboratorio SYNLAB, realiza ...

новости

a8046015ce41433bee06b10af7db0ceed5066e2c774f8379a21a4ab50bdc3e60
29/05/2020.
New care circuit for Covid-19 patients and special measures for attending to the vulnerable
With the aim of protecting both you and us, we have designed a ...

новости

Foto portada equip
25/05/2020.
El equipo del Institut de la Màcula te da las gracias!
 El Dr. Jordi Monés y todo el equipo del Institut de la Màcula en e...

новости

0
15/05/2020.
Dr. Monés comunica en este vídeo las nuevas medidas para afrontar los efectos del Covid-19
El doctor Jordi Monés, MD, PhD, comunica, en ...

новости

Исследования + подробнее

F6
14/02/2020.
Clinical trial OAKS-DERBY: efficacy and safety of APL-2 in the treatment of geographic atrophy secondary to AMD

 

IF YOU WANT TO PARTICIPATE IN A CLINICAL TRIAL, SEND US YOUR DATA HERE AND WE WILL EVALUATE IF YOU ARE ELEGIBLE

Description

This is a multicentre, randomised, double masked phase III clinical trial, controlled by simulated treatment. It compares the efficacy and safety of intravitreal APL-2 treatment with simulated injections in patients with geographic atrophy secondary to age-related macular degeneration.

Main inclusion criteria

Patients of 60 and above who present geographic atrophy secondary to age-related macular degeneration and who have not received any previous treatment in the study eye.

The size of the lesion should be between 2.5 and 17.5mm².

There must be hyper-autofluorescence and vision must be equal to or greater than 24 letters (approximate Snellen equivalent of 20/320).

Aim

The main aim will be to assess the efficacy of APL-2 compared to simulated injection in patients with geographic atrophy secondary to age-related macular degeneration, determined according to the change in lesion size at 12 months according to autofluorescence.

About the drug

The biochemical, genetic and clinical lines of evidence in humans indicate that the complement system plays a role in the etiology of age-related macular degeneration.

Complement protein C3 (which has a pro-inflammatory action), the membrane attack complex and complement factor H are present in drusen and in basal laminar deposits of patients with age-related macular degeneration.

APL-2 is a drug for intravitreal use that blocks the action of C3, its main action being anti-inflammatory.

The results of previous studies support the start of the phase III trial to assess the efficacy and safety of APL-2 in order to reduce the progression of geographic atrophy.

Duration

The duration of this trial is two and a half years (30 months).

* Institut Registration Code: E08607500. Clinica trial n. EudraCT 2018-001436-22 (study 303) and 2018-001435-52 (study 304). Clinical trial authorised by the Spanish Agency of Medicines and Medical Devices (AEMPS) and the CEIm of the Quironsalud Hospital Group in Barcelona.

IF YOU WANT TO PARTICIPATE IN A CLINICAL TRIAL, SEND US YOUR DATA HERE AND WE EVALUATE IF YOU ARE ELEGIBLE

 IDLM-53_2

...

Исследования наем

talon
26/11/2019.
TALON clinical trial: Efficacy and safety of brolacizumab in the treatment of exudative AMD

 

IF YOU WANT TO PARTICIPATE IN A CLINICAL TRIAL, SEND US YOUR DATA HERE AND WE WILL EVALUATE IF YOU ARE ELEGIBLE

Description

Multicentre, randomised double-blind Phase IIIb study to evaluate the efficacy and safety of brolacizumab 6mg compared to aflibercept 2mg in a treatment regimen until control in patients with the exudative form of age-related macular degeneration (AMD).

Main inclusion criteria

Patients of 50 and above with an active choroidal neovascularisation secondary to AMD and who have not received any previous treatment in the study eye.

Visual acuity should be between 38 and 83 letters (approximate Snellen equivalent of 20/25 to 20/200).

Aims

To evaluate the efficacy and safety of brolacizumab in comparison with aflibercept with regard to the results for visual acuity at 28 and 32 weeks in reference to the baseline, but also in terms of the duration of the intervals between treatments.

About the drug

Vascular endothelial growth factor (VEGF) is a glycoprotein with a trophic and proliferative role, promoting the growth of new filtering and abnormal blood vessels in the retina in patients with exudative AMD.

Brolacizumab (RTH258) is a humanised single-chain antibody fragment (scFv) that is responsible for blocking the action of VEFG-A, preventing it from binding to its receptors (VEGFR1 and VEGFR2) on the surface of endothelial cells, meaning that its principal function is anti-angiogenic. Brolacizumab is designed for ophthalmic use and administered by intravitreal injection.

Previous studies have produced results that support the commencing of a Phase IIIb trial in order to evaluate the safety and efficacy of brolacizumab in patients with neovascular AMD, with the aim of prolonging the therapeutic effect and enabling improved penetration of retinal tissue.

Duration

The duration of this trial is sixteen months.

* Institut Registration Code: E08607500. Clinica trial n. EudraCT 2019-000716-28. Clinical trial authorised by the Spanish Agency of Medicines and Medical Devices (AEMPS) and the CEIm of the Quironsalud Hospital Group in Barcelona.

IF YOU WANT TO PARTICIPATE IN A CLINICAL TRIAL, SEND US YOUR DATA HERE AND WE EVALUATE IF YOU ELEGIBLE

 IDLM-53_2

...

Исследования наем

IM_Captura-4-1024x681
13/11/2019.
Research project MICROBEYEOME

 

IF YOU WANT TO PARTICIPATE IN A CLINICAL TRIAL, SEND US YOUR DATA HERE AND WE WILL EVALUATE IF YOU ARE ELEGIBLE

Description

Age-related macular degeneration (AMD) is the leading cause of vision loss in people of over 50 in developed countries. Although the risk factors for the disease have been widely catalogued, its causes continue to be little known.

In recent years, there has been an exponential increase in research on the association between the intestinal microbiota and the diseases that affect humans.

Principal inclusion criteria

Patients of over 50, with age-related macular degeneration and healthy patients.

The patients must not have taken antibiotics in the past three months.

Patients with other neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease, or those in treatment for any type of cancer, will be excluded.

Aim

The MICROBEYEOME study attempts to characterise the intestinal and oral microbiome of the patients diagnosed with AMD through RNA 16S sequencing and compare it with the microbiome of healthy patients, thereby identifying whether a single microbial composition may be associated with a specific phenotype. Given that the intestinal microbiome is potentially modifiable, this study could open new avenues of research for the prevention and/or possible treatment of AMD.

Duration

This initial phase of the trial consists of a single visit.

Consortium partners

Institut de la Màcula
Barcelona Macula Foundation
 Centre for Genomic Regulation

 

...

Исследования наем

DMAE exsudativa (1)
09/04/2019.
LUCERNE clinical trial: efficacy and safety of FARICIMAB regarding aflibercept in the treatment of exudative age-related macular degeneration

IF YOU WANT TO PARTICIPATE IN A CLINICAL TRIAL, SEND US YOUR DATA HERE AND I WILL EVALUATE IF YOU ARE ELIGIBLE

Description

This is a multicentre, randomized and double-masking Clinical Trial Phase III of two parallel groups that evaluates the efficacy and safety of faricimab administered by intravitreal injeccions in patients with exudative age-related macular degenereation (AMD) compared to treatment with aflibercept (EYLEA®).

 Main inclusion criteria

Patients over 50 years of exudative age-related macular degeneration who have not received study’s treatment for this eye disease

Visual acuity should be between 20/32 and 20/320.

 Goal

The main objective is to demonstrate the efficacy of faricimab compared with aflibercept regarded the visual acuity result one year later

About the medicine

Faricimab is the first bispecific monoclonal antibody designed for intravitreal use that combines the antiangiogenic action of the medicine currently used for the AMD’s treatment with the anti-inflammatory action, neutralizing VEGF and angiopoietin-2 at the same time. The results in previous studies support the beginning of a Phase III trial to evaluate the efficacy and safety of faricimab in the treatment of neovascular AMD patients, in order to increase the intervals between treatments.

 Duration

This essay lasts for two years.

IF YOU WANT TO PARTICIPATE IN A CLINICAL TRIAL, SEND US YOUR DATA HERE AND I WILL EVALUATE IF YOU ARE ELIGIBLE

...

Исследования

Иностранные пациенты

Вы не являетесь жителем Барселоны, но желаете пройти курс лечения в нашем Институте? Здесь Вы найдете всю, интересующую вас информацию.

Помогите нам в борьбе с дегенеративными заболеваниями зрения. Фонд BMF ведет исследования по поиску эффективного лечения в случаях продвинутых стадий слепоты. Сотрудничайте с Barcelona Macula Foundation: Исследование Зрения Кнопка: Хочу сотрудничать

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Last modified: 30 July, 2020 - 10:01